Depp has just won the MTV Generation Award at the ceremony, which was hosted by Russell Brand, and was introduced by Steven Tyler and Joe Perry. After watching a montage of clips of his career in film, Depp joked: "This is getting out of the business award based on the observation of all clips is clearly something wrong with me.".
Other winners of the night were lovers in real life, Kristen Stewart and Robert Pattinson, who won for Best Kiss for the fourth consecutive year, with a kiss in The Twilight Saga: Breaking Dawn - Part 1, which was named Movie the Year.

Meanwhile, LMFAO scored the award for Best Music for 'Party Rock Anthem' from his track, which was presented in 21 Jump Street.